Testosterone Therapy (TRT) for Men in San Antonio

Testosterone therapy (TRT) is a prescription treatment for men whose bodies make too little testosterone, a condition called hypogonadism. At Yaso Wellness in San Antonio, Leticia Vargas, MD, prescribes it only after an exam and repeat morning blood tests confirm low levels. TRT has real risks and needs monitoring. Not every man is a candidate.

Key facts

Who it's for: adult men with symptoms of low testosterone and blood tests that confirm it.
Prescribed by: Leticia Vargas, MD, at our clinic at 1907 Goliad Rd, San Antonio, TX 78223.
Testing first: at least two early-morning blood tests on different days, as FDA labels and medical guidelines advise.
Controlled medicine: testosterone is a Schedule III controlled substance, with limits on refills.
Monitoring: blood tests and blood pressure checks before and during treatment.
Fertility: TRT can lower sperm count. Men who want children should say so before starting.

What is testosterone replacement therapy?

Testosterone is the main male sex hormone. It plays a part in sex drive, body hair, muscle, bone and red blood cell production. When the testicles, or the brain glands that signal them (the pituitary and hypothalamus), don't work as they should, testosterone levels can fall too low.

Testosterone replacement therapy gives back testosterone the body is not making. FDA approves testosterone products for men who have low testosterone linked to a medical condition, such as:

primary hypogonadism: the testicles don't make enough, for example after injury, infection, chemotherapy or a genetic condition such as Klinefelter syndrome;
secondary (hypogonadotropic) hypogonadism: the pituitary gland or hypothalamus doesn't send the right signals.

Who is a candidate for TRT?

The Endocrine Society advises diagnosing low testosterone only in men who have both symptoms and testosterone levels that are clearly and consistently low. It also advises against screening all men, and against giving testosterone to every older man with a low number. Treatment for men over 65 is decided one person at a time, after a full talk about risks and benefits.

TRT is usually not a good fit if you:

have breast cancer or known or suspected prostate cancer (current FDA labels);
are trying to father a child soon;
have uncontrolled high blood pressure;
have a very high red blood cell count;
have untreated severe sleep apnea.

How does TRT work at Yaso Wellness?

Evaluation. Dr. Vargas reviews your symptoms, health history, medicines and family plans, and does an exam.
Blood tests. Morning testosterone is checked on at least two separate days. Other tests may include LH and FSH (pituitary signals), prolactin, a blood count (hemoglobin and hematocrit) and, for men over 40, PSA, a prostate blood test.
Finding the cause. Some causes can be fixed without testosterone, such as a medicine side effect or a pituitary problem that needs its own care.
Shared decision. If you qualify, you and Dr. Vargas weigh the benefits and risks together.
Follow-up. Testosterone level, blood count, PSA and blood pressure are rechecked over time, and the dose is adjusted.

What forms of testosterone are FDA-approved?

FDA-approved testosterone comes in several forms, including:

gels applied to the skin each day;
injections into a muscle or under the skin;
skin patches;
capsules taken by mouth;
a product placed against the gum.

Each form has its own label, dose and risks. Gels can pass to women and children through skin contact, which is why they carry a boxed warning. Dr. Vargas helps you choose an FDA-approved form that fits your health and daily life.

What can TRT do, and what can't it do?

For men with confirmed hypogonadism, treatment may help symptoms linked to low testosterone, such as low sex drive. Results differ from man to man, and some symptoms have other causes, like poor sleep, depression, diabetes or weight.

FDA has not approved testosterone to boost energy, build muscle, improve sports performance or slow aging. Using more than prescribed can harm the heart, liver and mood. Read about the risks on our TRT side effects and safety page.

What changed with testosterone labels in 2025 and 2026?

In 2025, FDA added a blood pressure warning to all testosterone products and added results from the TRAVERSE heart-safety study. In June 2026, FDA asked drug makers to update labels again, including the wording about age-related low testosterone and prostate conditions. Labels change only after FDA approves the new text, so ask your clinician what applies to your medicine.

What to ask your clinician

Are my symptoms likely due to low testosterone, or something else?
What were my morning testosterone results on each test?
What is causing my low testosterone?
How will TRT affect my fertility?
Which form fits me, and what are its specific risks?
How often will I need blood tests and blood pressure checks?

Frequently asked questions

Does Yaso Wellness treat men? Yes, for testosterone therapy. Yaso Wellness is mainly a women's health clinic, and Dr. Vargas offers TRT to men with confirmed low testosterone.

Can I start TRT after one blood test? No. Testosterone changes through the day and from day to day. FDA labels call for morning tests on at least two separate days before treatment.

Is TRT safe? It can be used safely in the right patient with monitoring, but it has risks, including higher blood pressure, a high red blood cell count, blood clots and lower sperm count. See TRT side effects.

Will I need TRT for life? Many men with permanent hypogonadism stay on it long term. If the cause can be treated, testosterone may not be needed. Stopping should be planned with your clinician.

Can testosterone help with weight loss? Testosterone is not a weight-loss medicine. If weight is a concern, ask about our medical weight loss program.

Book a visit

Call (210) 903-1030 or Book a visit. In-clinic in San Antonio

About the clinician

Leticia Vargas, MD, OB/GYN, founder of Yaso Wellness Health Clinic. About Dr. Vargas

Sources

FDA, Testosterone Information (updated 6/23/2026): https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/testosterone-information (checked 2026-11-10)
FDA, FDA issues class-wide labeling changes for testosterone products (2025): https://www.fda.gov/drugs/drug-alerts-and-statements/fda-issues-class-wide-labeling-changes-testosterone-products (checked 2026-11-10)
FDA label, AndroGel 1% (testosterone gel), revised 7/2025 (boxed warning, two morning tests, contraindications): https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/021015s047lbl.pdf (checked 2026-11-10)
HHS, FDA Requests Updates to Testosterone Therapy Labeling (June 2026): https://www.hhs.gov/press-room/fda-requests-updates-testosterone-therapy-labeling.html (checked 2026-11-10)
Endocrine Society, Testosterone Therapy in Men With Hypogonadism, Clinical Practice Guideline (2018): https://www.endocrine.org/clinical-practice-guidelines/testosterone-therapy (checked 2026-11-10)
American Urological Association, Evaluation and Management of Testosterone Deficiency (2018, amended 2024): https://www.auanet.org/guidelines-and-quality/guidelines/testosterone-deficiency-guideline (checked 2026-11-10)
MedlinePlus, Testosterone Injection (controlled substance, fertility, monitoring): https://medlineplus.gov/druginfo/meds/a614041.html (checked 2026-11-10)

Education only, not medical advice or a diagnosis. In an emergency, call 911.